Tottenham have a dearth of attacking options, with Peter Crouch their only fit striker.
Jermain Defoe and Luka Modric are out with groin strains, Robbie Keane has a knee injury, and Roman Pavyluchenko and Giovani dos Santos are also sidelined.
Stoke
Doubtful: Jones (ankle) Injured: Lawrence (groin)
Tottenham
Injured: Bentley & Pavyluchenko (both ankle), Defoe, Modric & Woodgate (all groin), dos Santos (hamstring), Keane (knee), O'Hara (back)
MATCH PREVIEW
Taught a lesson by Young Boys in midweek, Tottenham can expect a searching examination on Saturday from an old-school team.
It is a very physical challenge at Stoke, like always, but we know that. We beat them last year and I think we can do it again this year
Spurs midfielder Luka Modric
Stoke are unashamedly direct and physical, and will try to bully a Spurs side that crashed in Berne on their Champions League debut.
This is also a meeting between pupil and mentor; Tony Pulis was a player, captain and coach under Harry Redknapp's supervision at Bournemouth before succeeding him as manager in 1992. The pair are now firm friends, and Pulis has even bought a house close to Redknapp at an exclusive retreat in Dorset.
Stoke have been right at home in the Premier League since promotion two years ago, earning two mid-table finishes. Their victory in this fixture in October 2008 resulted in the demise of Juande Ramos at Spurs, and a new dawn under Redknapp.
Tottenham have since graduated to a place among Europe's elite; how long they stay there depends on their response to a disappointing opening week of the season.
MATCH FACTS
Head-to-head
• Stoke's only win in their last four home league matches against Tottenham was in October 2008.
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Stoke
• Stoke have won their opening home match in each of their previous two years in the Premier League: 3-2 against Aston Villa in 2008 and 2-0 against Burnley last season.
• They have won one of their last seven league matches since April (W1, D2, L4).
• The Potters lost 22 points from winning positions last season. Only Wigan Athletic had a worse record in the top flight.
• Danny Higginbotham is expected to make his 200th Premier League appearance.
• Matthew Etherington will be playing against his former club.
Tottenham
• Tottenham have lost three of their last four Premier League away matches, conceding 10 goals.
• On Tuesday night, Spurs conceded three goals in a European match for the first time in 61 games since a 4-1 defeat to Bayern Munich in 1982.
• Roman Pavlyuchenko is the club's top Premier League scorer in 2010 with five goals, one more than Jermain Defoe and Peter Crouch.
• Defoe is a hat-trick shy of 100 Premier League goals.
LEADING GOALSCORERS
Stoke
Abdoulaye Faye: 1 goal (1 league)
Tottenham
Bassong & Pavlyuchenko: 1 goal (0 league)
MATCH OFFICIALS
Referee: Chris Foy
Assistant referees: Bob Pollock & Martin Yerby
Fourth official: Mark Halsey
LAST LEAGUE MATCH LINE-UPS
Stoke (L1-2 v Wolves, a): Sorensen; Huth, Abdoulaye Faye, Shawcross, Higginbotham, Delap, Whitehead, Whelan (Tonge 67), Etherington, Jones (Sidibe 14, Sanli 51), Fuller. Subs not used: Begovic, Collins, Pugh, Wilkinson.
Tottenham (D0-0 v Man City, h): Gomes; Corluka, Dawson, King, Assou-Ekotto, Lennon (Giovani 77), Modric, Huddlestone, Bale, Crouch (Keane 68), Defoe (Pavlyuchenko 68). Subs not used: Cudicini, Kaboul, Palacios, Bassong.
Source: BBC Sport
Source: BBC Sport