The Potters have hosted some of the best sides in the world since their promotion to the Premier League in 2007/08, but Pulis reckons Saturday's clash with Ian Holloway's men will surpass many of those.
He said: "Blackpool are a fluent team. They're very organised and everybody knows their jobs. It's going to be a tough, tough game for us.
"I think it will be one of our toughest games at the Britannia, for two reasons.
"Firstly, it's one of the few occasions that we will be favourites, and secondly, the fact that they are such a well-drilled, fit, organised team."
Source: PA
Source: PA